Article

Synaptic networks shape clinical phenotypes in neurodevelopmental disorders: An integrative clinical, genetic and biological perspective

2026-01-23

Abstract excerpt

<h4>Background</h4> Clinical variability in synaptopathies suggests complex multidimensional interactions. The resulting phenotypes depend not only on the affected gene, but also on its functional role, subcellular localization, and spatiotemporal brain expression, among other potential influencing factors. Here, we present a proof of concept integrating genetic, synaptic, and developmental expression data to exp...

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Literature Corpus work: e6e6c9fa-df5d-5088-a6e4-a7242dee7419
DOI: 10.64898/2026.01.23.701319

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