Article
A proteogenomic tool uncovers protein markers for human microglial states
2025-04-04
Abstract excerpt
Human microglial heterogeneity has been largely described using transcriptomic data. Here, we introduce a microglial proteomic data resource and a Cellular Indexing of Transcriptomes and Epitopes by Sequencing panel enhanced with antibodies targeting 17 microglial cell surface proteins (mCITE-Seq). We evaluated mCITE-Seq on HMC3 microglia-like cells, induced-pluripotent stem cell-derived microglia (iMG), and fresh...
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Identifiers and source
- Literature Corpus work
- 781f7a88-2304-501a-aa69-1f7e9185eedd
- DOI
- 10.1101/2025.03.31.646212