Article

The glia club: Validation of polarization biomarkers for human microglia (HMC3) using quantitative real time RT-qPCR

2024-09-26

Abstract excerpt

Microglia are the primary immune cells of the brain and play critical roles in neurodevelopment, neuroprotection, the maintenance of homeostasis, and neurotoxicity. Classification of microglia polarization, however, remains contentious. Identifying suitable biomarkers for gene expression analysis of microglia polarization is crucial for characterizing the biological significance of microglia in health and disease....

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 3b8575e4-3358-52ed-ba97-9979c97c1ec6
DOI: 10.1101/2024.09.26.615202

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The glia club: Validation of polarization biomarkers for human microglia (HMC3) using quantitative real time RT-qPCRDOI 10.1101/2024.09.26.615202Read

Transcriptional benchmarking of human monocyte-derived microglia-like cells and iPSC-derived microglia reveals distinct immune-alert and homeostatic programmesSemantic proximity Read

The Human Microglia Atlas (HuMicA) Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative ConditionsSemantic proximity Read

The human microglia responsome: a resource to better understand microglia states in health and diseaseSemantic proximity Read

The Human Microglia Atlas (HuMicA) Unravels Changes in Homeostatic and Disease-Associated Microglia Subsets across Neurodegenerative ConditionsSemantic proximity Read

The human microglia responsome: a resource to better understand microglia states in health and diseaseSemantic proximity Read

Analyzing microglial phenotypes across neuropathologies: a practical guide.Semantic proximity Read

In Search for Reliable Markers of Glioma-Induced Polarization of MicrogliaSemantic proximity Read

Microglia/macrophage polarization: Fantasy or evidence of functional diversity?Semantic proximity Read

Decoding Microglial Polarization and Metabolic Reprogramming in Neurodegenerative Diseases: Implications for Disease Progression and TherapySemantic proximity Read

Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signaturesSemantic proximity Read

Modulating the polarization phenotype of microglia - A valuable strategy for central nervous system diseases.Semantic proximity Read

A proteogenomic tool uncovers protein markers for human microglial statesSemantic proximity Read