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Single‐cell transcriptomics reveals distinct inflammation‐induced microglia signatures

11 Sept 2018

Abstract excerpt

Microglia are specialized parenchymal-resident phagocytes of the central nervous system (CNS) that actively support, defend and modulate the neural environment. Dysfunctional microglial responses are thought to worsen CNS diseases; nevertheless, their impact during neuroinflammatory processes remains largely obscure. Here, using a combination of single-cell RNA sequencing and multicolour flow cytometry, we...

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PMID: 30206190
DOI: 10.15252/embr.201846171

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