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A proteogenomic tool uncovers protein markers for human microglial states

2025-05-02

Abstract excerpt

<title>Abstract</title> <p>Human microglial heterogeneity has been largely described using transcriptomic data. Here, we introduce a microglial proteomic data resource and a Cellular Indexing of Transcriptomes and Epitopes by Sequencing panel enhanced with antibodies targeting 17 microglial cell surface proteins (mCITE-Seq). We evaluated mCITE-Seq on HMC3 microglia-like cells, induced-pluripotent stem cell-derive...

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Literature Corpus work
53b52b1b-0174-555e-a705-eed4df04f326
DOI
10.21203/rs.3.rs-6380446/v1
Open publication

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A proteogenomic tool uncovers protein markers for human microglial statesDOI 10.21203/rs.3.rs-6380446/v1
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