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Combining xQTL and genome-wide association studies from ethnically diverse populations improves druggable gene discovery

2025-05-28

Abstract excerpt

<title>Abstract</title> <p>Repurposing existing medicines to target disease-associated genes represents a promising strategy for developing new treatments for complex diseases. However, progress has been hindered by a lack of viable candidate drug targets identified through genome-wide association studies (GWAS). Gene-based association tests provide a more powerful alternative to traditional single nucleotide pol...

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Literature Corpus work
11e9f60a-4877-5963-9327-d81d898195bf
DOI
10.21203/rs.3.rs-6700169/v1
Open publication

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Combining xQTL and genome-wide association studies from ethnically diverse populations improves druggable gene discoveryDOI 10.21203/rs.3.rs-6700169/v1
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