Article

Dynein-Powered Cell Locomotion Guides Metastasis of Breast Cancer

2023-04-06

Abstract excerpt

<h4>ABSTRACT</h4> Metastasis is a principal cause of death in cancer patients, which remains an unresolved fundamental and clinical problem. Conventionally, metastatic dissemination is linked to the actomyosin-driven cell locomotion. However, locomotion of cancer cells often does not strictly line up with the measured actomyosin forces. Here, we identify a complementary mechanism of metastatic locomotion powered...

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Literature Corpus work: 11d3ea34-534a-5d3d-a000-4935c2811790
DOI: 10.1101/2023.04.04.535605

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