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Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironments

2020-04-23

Abstract excerpt

<h4>ABSTRACT</h4> Defining the principles of T cell migration in structurally and mechanically complex tumor microenvironments is critical to understanding sanctuaries from antitumor immunity and optimizing T cell-related therapeutic strategies. To enhance T cell migration through complex microenvironments, we engineered nanotextured platforms that allowed us to define how the balance between T cell phenotypes in...

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Identifiers and source

Literature Corpus work
40e17e83-e33d-5747-bff8-8efd5fa29a14
DOI
10.1101/2020.04.21.051615
Open publication

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Engineering T cells to enhance 3D migration through structurally and mechanically complex tumor microenvironmentsDOI 10.1101/2020.04.21.051615
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