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Article

Interstitial flows promote amoeboid over mesenchymal motility of breast cancer cells revealed by a three dimensional microfluidic model.

Integrative biology : quantitative biosciences from nano to macro - 1 Nov 2015

Huang Yu Ling, Tung Chih-Kuan, Zheng Anqi, Kim Beum Jun, Wu Mingming

Abstract excerpt

Malignant tumors are often associated with an elevated fluid pressure due to the abnormal growth of vascular vessels, and thus an increased interstitial flow out of the tumors. Recent in vitro works revealed that interstitial flows critically regulated tumor cell migration within a three dimensional biomatrix, and breast cancer cell migration behavior depended sensitively on the cell seeding density, chemokine...

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Identifiers

PMID: 26235230
DOI: 10.1039/c5ib00115c
PMCID: PMC4630101

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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