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Article

Refining fine-mapping: effect sizes and regional heritability

2018-05-10

Abstract excerpt

Recent statistical approaches have shown that the set of all available genetic variants explains considerably more phenotypic variance of complex traits and diseases than the individual variants that are robustly associated with these phenotypes. However, rapidly increasing sample sizes constantly improve detection and prioritization of individual variants driving the associations between genomic regions and pheno...

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Literature Corpus work
11780941-2e27-5588-8b46-c686f376277c
DOI
10.1101/318618
Open publication

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Refining fine-mapping: effect sizes and regional heritabilityDOI 10.1101/318618
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