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Article

From genome-wide associations to candidate causal variants by statistical fine-mapping.

Nature reviews. Genetics - 1 Aug 2018

Schaid Daniel J, Chen Wenan, Larson Nicholas B

Abstract excerpt

Advancing from statistical associations of complex traits with genetic markers to understanding the functional genetic variants that influence traits is often a complex process. Fine-mapping can select and prioritize genetic variants for further study, yet the multitude of analytical strategies and study designs makes it challenging to choose an optimal approach. We review the strengths and weaknesses of...

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PMID: 29844615
DOI: 10.1038/s41576-018-0016-z
PMCID: PMC6050137

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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