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Article

Fine-mapping genetic associations.

Human molecular genetics - 30 Sept 2020

Hutchinson Anna, Asimit Jennifer, Wallace Chris

Abstract excerpt

Whilst thousands of genetic variants have been associated with human traits, identifying the subset of those variants that are causal requires a further 'fine-mapping' step. We review the basic fine-mapping approach, which is computationally fast and requires only summary data, but depends on an assumption of a single causal variant per associated region which is recognized as biologically unrealistic. We discuss...

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Identifiers

PMID: 32744321
DOI: 10.1093/hmg/ddaa148
PMCID: PMC7733401

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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