Article
Fine Mapping Causal Variants with an Approximate Bayesian Method Using Marginal Test Statistics.
Genetics - 1 Jul 2015
Chen Wenan, Larrabee Beth R, Ovsyannikova Inna G, Kennedy Richard B, Haralambieva Iana H, Poland Gregory A, Schaid Daniel J
Abstract excerpt
Two recently developed fine-mapping methods, CAVIAR and PAINTOR, demonstrate better performance over other fine-mapping methods. They also have the advantage of using only the marginal test statistics and the correlation among SNPs. Both methods leverage the fact that the marginal test statistics asymptotically follow a multivariate normal distribution and are likelihood based. However, their relationship with...
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