Article

Single-Cell Phylogenetic Tracing Maps the Landscape of Human Tumor Immune Cell Plasticity Driven by Microenvironment Factors-Mediated Epigenetic Reprogramming

2023-04-28

Abstract excerpt

The tumor microenvironment harbors a complex ecosystem of immune cells, the heterogeneity of which has been extensively characterized, yet the developmental trajectories and plasticity of these populations remain poorly understood. Here, by integrating mitochondrial DNA mutations and chromosomal single-nucleotide polymorphisms inferred from single-cell RNA sequencing data, we established a robust lineage tracing f...

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Literature Corpus work: dfc6de6e-ac24-51fd-942a-cae9ce6a1fbf
DOI: 10.1101/2023.04.28.538645

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Single-Cell Phylogenetic Tracing Maps the Landscape of Human Tumor Immune Cell Plasticity Driven by Microenvironment Factors-Mediated Epigenetic ReprogrammingDOI 10.1101/2023.04.28.538645Read

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