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Type I IFN Signaling Limits Hemorrhage-Like Disease After Infection With Japanese Encephalitis Virus Through Modulating A Prerequisite Infection of CD11b+Ly-6C+ Monocytes

2020-12-16

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The crucial role of type I interferon (IFN-I, IFN-a/b) is well known to control central nervous system (CNS)-neuroinflammation caused by neurotrophic flaviviruses such as Japanese encephalitis virus (JEV) and West Nile virus. However, an in-depth analysis of IFN-I signal-dependent cellular factors that govern CNS-restricted tropism in JEV infection in vivo remai...

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Literature Corpus work
111dc5c6-2fe6-5809-a544-83102dd9cf79
DOI
10.21203/rs.3.rs-126754/v1
Open publication

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Type I IFN Signaling Limits Hemorrhage-Like Disease After Infection With Japanese Encephalitis Virus Through Modulating A Prerequisite Infection of&nbsp;CD11b+Ly-6C+ MonocytesDOI 10.21203/rs.3.rs-126754/v1
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