Article
Interleukin-17A released from intestinal γδT cells induces cytokine storm in mice with severe dengue
2022-09-16
Abstract excerpt
<title>Abstract</title> <p>Blockade of TNF-α signaling protects mice from lethal infection with dengue virus (DENV); however, what causes cytokine storm or how TNF-α aggravates the disease remains unknown. Here, we performed transcriptome analysis of the liver and small intestine samples collected chronologically from DENV-3 P12/08-infected IFN-α/β and γ receptor knockout (IFN-α/β/γRKO) mice in the presence/absen...
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Identifiers and source
- Literature Corpus work
- da6aaac6-2c61-567e-b6b0-51ea34ed83a3
- DOI
- 10.21203/rs.3.rs-1983205/v1
