Article

Conserved and cell type-specific transcriptional responses to IFN-γ in the ventral midbrain

2022-12-15

Abstract excerpt

Dysregulated inflammation within the central nervous system (CNS) contributes to neuropathology in infectious, autoimmune, and neurodegenerative disease. With the exception of microglia, major histocompatibility complex (MHC) proteins are virtually undetectable in the mature, healthy central nervous system (CNS). Neurons have generally been considered incapable of antigen presentation, and although interferon gamm...

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Literature Corpus work: 8d19ff88-814c-5de9-8fc4-eed1ca2c77fe
DOI: 10.1101/2022.12.14.520294

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