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Article

Divergent clonal evolution and tumor microenvironment remodeling shape gastric cancer peritoneal metastasis.

Communications biology - 25 Mar 2026

Charton Clémentine, Kang So Hyun, Kim Stephanie S, Kang Minsu, Lee Ju Hyun, Park Young Suk, Ahn Sang-Hoon, Suh Yun-Suhk, Kwon Nak Jung, Park Kyoung Un, Lee Jieun, Kim Jinho, Kim Hyung-Ho

Abstract excerpt

Gastric cancer peritoneal metastasis (GCPM) is a distinct clinical entity with a poor prognosis, characterized by aggressive features and limited treatment options. Understanding its molecular biology is critical for developing effective therapies. We performed whole genome and transcriptome sequencing on GCPM samples and partially paired primary gastric cancer (GC) tissues from 14 and 26 patients, respectively....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 41882239
DOI: 10.1038/s42003-026-09906-2
PMCID: PMC13181027

Genes

GC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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