Article

Immunomodulatory mechanisms of submicron phosphatidylserine-exposing polymeric particles (PSPs)

2026-08-10

Abstract excerpt

Macrophages are highly dynamic cells that maintain tissue homeostasis by regulating both initiation and resolution of inflammation. During efferocytosis, macrophages recognize the ‘eat me’ signal, phosphatidylserine (PS), exposed at the surface of apoptotic cells, leading to the resolution of inflammation and acquisition of a pro-resolving phenotype. Inspired by this endogenous mechanism, PS-based biomaterials hav...

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Literature Corpus work: 1109be38-c623-5a6c-a890-d70dd35e0827
DOI: 10.64898/2026.08.07.743390

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