Article

Platelet-derived exosomes in situ reprogramming macrophages for rheumatoid arthritis treatment

2025-08-08

Abstract excerpt

<title>Abstract</title> <p>M1 macrophages secrete various pro-inflammatory cytokines and play a pivotal role in the pathogenesis of rheumatoid arthritis (RA). Therefore, strategies aimed at eliminating synovial M1 macrophages or reprogramming them toward an anti-inflammatory M2 phenotype represent critical approaches for RA treatment. In this study, we propose a novel therapeutic strategy using platelet-derived e...

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Literature Corpus work: ba78c1bf-d459-58c9-9d37-658100af1df4
DOI: 10.21203/rs.3.rs-7169171/v1

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