Article

Bioactive Co-assembly of PSA/dit-VES Nanomicelles Orchestrates Macrophage Reprogramming for Acute Lung Injury Therapy

2026-01-30

Abstract excerpt

<title>Abstract</title> <p> Acute lung injury (ALI) is a clinical emergency characterized by uncontrolled inflammatory cascades and oxidative stress, in which the dysregulation of macrophage polarization plays a pivotal role. Although flavonoid-based phytochemical anti-inflammatory agents hold promise for inhibiting NF-κB signaling and scavenging reactive oxygen species (ROS), their clinical efficacy is hampered...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 44652c10-1f1d-54b7-956f-221195ec26a6
DOI: 10.21203/rs.3.rs-8608145/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Bioactive Co-assembly of PSA/dit-VES Nanomicelles Orchestrates Macrophage Reprogramming for Acute Lung Injury TherapyDOI 10.21203/rs.3.rs-8608145/v1Read

Peritoneal M2 macrophage-derived extracellular vesicles as natural multi-target nanotherapeutics to attenuate cytokine storm after severe infectionsSemantic proximity Read

Immunomodulatory mechanisms of submicron phosphatidylserine-exposing polymeric particles (PSPs)Semantic proximity Read

Bioactive Metal-Phenolic Network and Prebiotic Hydrogel Synergize with Mesenchymal stem cell-derived extracellular vesicles for Microenvironment-Modulating Therapy of Inflammatory Bowel DiseaseSemantic proximity Read

Extracellular Vesicle-Enriched Secretome from Mesenchymal Stromal Cells Protects Against Chemically, Particulate-, and Ischemia-Induced Innate-Immunity Induced InflammationSemantic proximity Read

Exosomes of different cellular origins: prospects and challenges in the treatment of acute lung injury after burnsSemantic proximity Read

Comparative Analysis of Liposomal and Surfactant-Based Drug Delivery SystemsSemantic proximity Read

Enhancing Therapeutic Outcomes with Smart Drug CarriersSemantic proximity Read

Construction, Phenotypic Characterization, and Immunomodulatory Function Study of BMSC-Macrophage Hybrid in vitroSemantic proximity Read

Multi-mechanistic mitochondria-mediated N-methylated YKWYYRGAA-decorated nano-chitosan conjugate carrier for treatment of NRAS-mutant-harbouring lung carcinoma.Semantic proximity Read

Zwitterionic Inhaler with Synergistic Therapeutics for Reprogramming of M2 Macrophage to Pro-Inflammatory Phenotype.Semantic proximity Read

Advancements in Nanoceria for Immunotherapy ApplicationsSemantic proximity Read

Microneedles loaded with cerium-manganese oxide nanoparticles for targeting macrophages in the treatment of rheumatoid arthritisSemantic proximity Read