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Article

Macrophage-related therapeutic strategies: Regulation of phenotypic switching and construction of drug delivery systems.

Pharmacological research - 1 Jan 2024

Wang Xi, Li Yixuan, Pu Xueyu, Liu Guiquan, Qin Honglin, Wan Weimin, Wang Yuying, Zhu Yan, Yang Jian

Abstract excerpt

Macrophages, as highly phenotypic plastic immune cells, play diverse roles in different pathological conditions. Changing and controlling the phenotypes of macrophages is considered a novel potential therapeutic intervention. Meanwhile, specific transmembrane proteins anchoring on the surface of the macrophage membrane are relatively conserved, supporting its functional properties, such as inflammatory chemotaxis...

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PMID: 38043691
DOI: 10.1016/j.phrs.2023.107022

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