Article

The Relationship of Duffy Gene Polymorphism, High Sensitivity C-Reactive Protein, and Long-term Outcomes

2023-08-08

Abstract excerpt

<h4>Background</h4> Black adults have higher incidence of all-cause death and worse cardiovascular outcomes when compared to other populations. The Duffy chemokine receptor is not expressed in a large majority of Black adults and the clinical implications of this are unclear. <h4>Methods</h4> Here, we investigated the relationship of Duffy receptor status, high-sensitivity C-reactive protein (hs-CRP), and long-ter...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 1108ec99-88c9-5353-b5e8-8b7658ba954f
DOI: 10.1101/2023.08.03.23293626

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

The Relationship of Duffy Gene Polymorphism, High Sensitivity C-Reactive Protein, and Long-term OutcomesDOI 10.1101/2023.08.03.23293626Read

The Relationship of Duffy Gene Polymorphism with High-Sensitivity C-Reactive Protein, Mortality, and Cardiovascular Outcomes in Black Individuals.Semantic proximity Read

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators.Semantic proximity Read

Reduced neutrophil count in people of African descent is due to a regulatory variant in the Duffy antigen receptor for chemokines gene.Semantic proximity Read

Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.Semantic proximity Read

Characterization of the phenotypic consequences of the Duffy-null genotypeSemantic proximity Read

The association between a Darc gene polymorphism and clinical outcomes in African American patients with acute lung injury.Semantic proximity Read

Distinct Transcript Isoforms of the Atypical Chemokine Receptor 1 (ACKR1)/Duffy Antigen Receptor for Chemokines (DARC) Gene Are Expressed in Lymphoblasts and Altered Isoform Levels Are Associated with Genetic Ancestry and the Duffy-Null Allele.Semantic proximity Read

Duffy antigen receptor genetic variant and the association with Interleukin 8 levels.Semantic proximity Read

The Duffy antigen modifies systemic and local tissue chemokine responses following lipopolysaccharide stimulation.Semantic proximity Read

Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean.Semantic proximity Read

Absolute neutrophil count by Duffy status among healthy Black and African American adultsSemantic proximity Read

Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.Semantic proximity Read