Article
The Relationship of Duffy Gene Polymorphism with High-Sensitivity C-Reactive Protein, Mortality, and Cardiovascular Outcomes in Black Individuals.
Genes - 27 Oct 2024
Ha Edward T, Haessler Jeffery, Taylor Kent D, Tuftin Bjoernar, Briggs Matt, Parikh Manish A, Peterson Stephen J, Gerszten Robert E, Wilson James G, Kelsey Karl, Tahir Usman A, Seeman Teresa, Rich Stephen S, Carson April P, Post Wendy S, Kooperberg Charles, Rotter Jerome I, Raffield Laura M, Auer Paul, Reiner Alex P
Abstract excerpt
Background: Black adults have higher incidence of all-cause mortality and worse cardiovascular disease (CVD) outcomes when compared to other U.S. populations. The Duffy chemokine receptor is not expressed on erythrocytes in a large majority of Black adults, but the clinical implications of this are unclear. Methods: Here, we investigated the relationship of Duffy receptor status, high-sensitivity C-reactive...
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