Article
Duffy-null-associated low neutrophil counts influence HIV-1 susceptibility in high-risk South African black women.
Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 1 May 2011
Ramsuran Veron, Kulkarni Hemant, He Weijing, Mlisana Koleka, Wright Edwina J, Werner Lise, Castiblanco John, Dhanda Rahul, Le Tuan, Dolan Matthew J, Guan Weihua, Weiss Robin A, Clark Robert A, Karim Salim S Abdool, Ahuja Sunil K, Ndung'u Thumbi
Abstract excerpt
BACKGROUND: The Duffy-null trait and ethnic netropenia are both highly prevalent in Africa. The influence of pre-seroconversion levels of peripheral blood cell counts (PBCs) on the risk of acquiring human immunodeficiency virus (HIV)-1 infection among Africans is unknown. METHODS: The triangular relationship among pre-seroconversion PBC counts, host genotypes, and risk of HIV acquisition was determined in a...
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