Article
Genome-wide association replicates the association of Duffy antigen receptor for chemokines (DARC) polymorphisms with serum monocyte chemoattractant protein-1 (MCP-1) levels in Hispanic children.
Cytokine - 1 Dec 2012
Voruganti V Saroja, Laston Sandra, Haack Karin, Mehta Nitesh R, Smith C Wayne, Cole Shelley A, Butte Nancy F, Comuzzie Anthony G
Abstract excerpt
Obesity is associated with a chronic low inflammatory state characterized by elevated levels of chemokines. Monocyte chemoattractant protein-1 (MCP-1) is a member of the cysteine-cysteine (CC) chemokine family and is increased in obesity. The purpose of this study was to identify loci regulating serum MCP-1 in obese Hispanic children from the Viva La Familia Study. A genome-wide association (GWA) analysis was...
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