Article
Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean.
British journal of haematology - 1 Oct 2008
Grann Victor R, Ziv Elad, Joseph Cecil K, Neugut Alfred I, Wei Ying, Jacobson Judith S, Horwitz Marshall S, Bowman Natalie, Beckmann Kenneth, Hershman Dawn L
Abstract excerpt
Neutropenia associated with race/ethnicity has essentially been unexplained and, although thought to be benign, may affect therapy for cancer or other illnesses. A recent study linked a single nucleotide polymorphism (SNP) (rs2814778) in the Duffy antigen/receptor chemokine gene (DARC) with white blood cell count. We therefore analysed the association of the rs2814778 CC, TC and TT genotypes with absolute...
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