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Article

Duffy antigen receptor for chemokines (Darc) polymorphism regulates circulating concentrations of monocyte chemoattractant protein-1 and other inflammatory mediators.

Blood - 1 Jul 2010

Schnabel Renate B, Baumert Jens, Barbalic Maja, Dupuis Josée, Ellinor Patrick T, Durda Peter, Dehghan Abbas, Bis Joshua C, Illig Thomas, Morrison Alanna C, Jenny Nancy S, Keaney John F, Gieger Christian, Tilley Cathy, Yamamoto Jennifer F, Khuseyinova Natalie, Heiss Gerardo, Doyle Margaret, Blankenberg Stefan, Herder Christian, Walston Jeremy D, Zhu Yanyan, Vasan Ramachandran S, Klopp Norman, Boerwinkle Eric, Larson Martin G, Psaty Bruce M, Peters Annette, Ballantyne Christie M, Witteman Jacqueline C M, Hoogeveen Ron C, Benjamin Emelia J, Koenig Wolfgang, Tracy Russell P

Abstract excerpt

To identify the genetic basis of circulating concentrations of monocyte chemoattractant protein-1 (MCP-1), we conducted genome-wide association analyses for MCP-1 in 3 independent cohorts (n = 9598). The strongest association was for serum MCP-1 with a nonsynonymous polymorphism, rs12075 (Asp42Gl...

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Identifiers

PMID: 20040767
DOI: 10.1182/blood-2009-05-221382
PMCID: PMC2902130

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20040767-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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