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Article

Characterization of the phenotypic consequences of the Duffy-null genotype

18 Jan 2025

Abstract excerpt

ABSTRACT: A wealth of research focused on African American populations has connected rs2814778-CC ("Duffy-null") to decreased neutrophil (neutropenia) and leukocyte counts (leukopenia). Although it has been proposed that this variant is benign, prior studies have shown that the misinterpretation of Duffy-null-associated neutropenia and leukopenia can lead to unnecessary bone marrow biopsies, inequities in...

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PMID: 39825822
DOI: 10.1182/bloodadvances.2024014399

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