Article

fSuSiE enables fine-mapping of QTLs from genome-scale molecular profiles

2025-08-17

Abstract excerpt

Molecular quantitative trait locus (QTL) studies seek to identify the causal variants affecting molecular traits like DNA methylation and histone modifications. However, existing fine-mapping tools are not well suited to high-dimensional molecular traits, and so analyses of these traits typically proceed by considering each variant and each molecular measurement independently, ignoring the LD among variants and th...

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Literature Corpus work: 1093673e-7030-5053-b798-6a26f8901d93
DOI: 10.1101/2025.08.17.670732

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