Article

Improved methods for multi-trait fine mapping of pleiotropic risk loci

2016-05-21

Abstract excerpt

Genome-wide association studies (GWAS) have identified thousands of regions in the genome that contain genetic variants that increase risk for complex traits and diseases. However, the variants uncovered in GWAS are typically not biologicaly causal, but rather, correlated to the true causal variant through linkage disequilibrium (LD). To discern the true causal variant(s), a variety of statistical fine-mapping met...

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Literature Corpus work: 01f6406d-e3a6-5976-b552-f76f3ec23826
DOI: 10.1101/054684

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