Article

Fine-mapping across diverse ancestries drives the discovery of putative causal variants underlying human complex traits and diseases

2023-01-09

Abstract excerpt

Genome-wide association studies (GWAS) of human complex traits or diseases often implicate genetic loci that span hundreds or thousands of genetic variants, many of which have similar statistical significance. While statistical fine-mapping in individuals of European ancestries has made important discoveries, cross-population fine-mapping has the potential to improve power and resolution by capitalizing on the gen...

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Literature Corpus work: 88611bbe-e844-54eb-8c47-4a9ee0d77acc
DOI: 10.1101/2023.01.07.23284293

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