Article

Gene selection by incorporating genetic networks into case-control association studies

2022-03-13

Abstract excerpt

Large-scale genome-wide association studies (GWAS) have been successfully applied to a wide range of genetic variants underlying complex diseases. The network-based penalized regression approach has been developed to overcome the challenges caused by the computational efficiency for analyzing high-dimensional genomic data by incorporating a biological genetic network. In this paper, we propose a gene selection app...

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Literature Corpus work: 105a8e33-ed1f-5089-8899-cdeeb8c26daa
DOI: 10.1101/2022.03.10.483891

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