Article
Evaluation of Penalized and Nonpenalized Methods for Disease Prediction with Large-Scale Genetic Data.
BioMed research international - 1 Jan 2015
Won Sungho, Choi Hosik, Park Suyeon, Lee Juyoung, Park Changyi, Kwon Sunghoon
Abstract excerpt
Owing to recent improvement of genotyping technology, large-scale genetic data can be utilized to identify disease susceptibility loci and this successful finding has substantially improved our understanding of complex diseases. However, in spite of these successes, most of the genetic effects for many complex diseases were found to be very small, which have been a big hurdle to build disease prediction model....
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