Article
Gene selection by incorporating genetic networks into case-control association studies.
European journal of human genetics : EJHG - 1 Mar 2024
Cao Xuewei, Liang Xiaoyu, Zhang Shuanglin, Sha Qiuying
Abstract excerpt
Large-scale genome-wide association studies (GWAS) have been successfully applied to a wide range of genetic variants underlying complex diseases. The network-based regression approach has been developed to incorporate a biological genetic network and to overcome the challenges caused by the computational efficiency for analyzing high-dimensional genomic data. In this paper, we propose a gene selection approach...
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