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Article

Network-based regularization for high dimensional SNP data in the case-control study of Type 2 diabetes.

BMC genetics - 16 May 2017

Ren Jie, He Tao, Li Ye, Liu Sai, Du Yinhao, Jiang Yu, Wu Cen

Abstract excerpt

BACKGROUND: Over the past decades, the prevalence of type 2 diabetes mellitus (T2D) has been steadily increasing around the world. Despite large efforts devoted to better understand the genetic basis of the disease, the identified susceptibility loci can only account for a small portion of the T2D heritability. Some of the existing approaches proposed for the high dimensional genetic data from the T2D...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28511641
DOI: 10.1186/s12863-017-0495-5
PMCID: PMC5434559

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