Article

Integrating network annotation from multiple correlated traits to improve polygenic risk scores based on GWAS summary statistics

2026-04-13

Abstract excerpt

<title>Abstract</title> <p>Polygenic risk scores (PRS) are valuable tools for predicting disease risk based on genetic information, with potential impacts on disease prevention and early treatment strategies. Although thousands of disease-associated genetic variants have been identified through genome-wide association studies (GWAS), the accuracy of genetic risk prediction for most diseases remains moderate and c...

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Literature Corpus work: e016d7a4-8e93-5e96-a116-8077d0842fd4
DOI: 10.21203/rs.3.rs-9073777/v1

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