Article
Network.assisted analysis to prioritize GWAS results: principles, methods and perspectives.
Human genetics - 1 Feb 2014
Jia Peilin, Zhao Zhongming
Abstract excerpt
Genome-wide association studies (GWAS) have rapidly become a powerful tool in genetic studies of complex diseases and traits. Traditionally, single marker-based tests have been used prevalently in GWAS and have uncovered tens of thousands of disease-associated SNPs. Network-assisted analysis (NAA) of GWAS data is an emerging area in which network-related approaches are developed and utilized to perform advanced...
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