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Article

Penalized logistic regression for high-dimensional DNA methylation data with case-control studies.

Bioinformatics (Oxford, England) - 15 May 2012

Sun Hokeun, Wang Shuang

Abstract excerpt

MOTIVATION: DNA methylation is a molecular modification of DNA that plays crucial roles in regulation of gene expression. Particularly, CpG rich regions are frequently hypermethylated in cancer tissues, but not methylated in normal tissues. However, there are not many methodological literatures of case-control association studies for high-dimensional DNA methylation data, compared with those of microarray gene...

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Identifiers

PMID: 22467913
DOI: 10.1093/bioinformatics/bts145
PMCID: PMC3348559

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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