Article

MutPrior:An Ensemble Method for Ranking Genes in Cancer

2016-06-10

Abstract excerpt

Root cause analysis of cancer as well of design of personalized treatment depends on the ability to prioritize mutated genes in cancer. In this paper, we propose a novel approach 'MutPrior' to prioritize genes in a given caner. We hypothesize that a gene is important for cancer if it has high functional impact mutations, is strategically important for network stability and has high relevance to the disease. This a...

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Literature Corpus work: aae0d939-6e42-5e26-ae70-da5cdb0fcb89
DOI: 10.1101/058222

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