Article

Single-nuclei transcriptomics of schizophrenia prefrontal cortex primarily implicates neuronal subtypes

2020-07-29

Abstract excerpt

Transcriptomic studies of bulk neural tissue homogenates from persons with schizophrenia and controls have identified differentially expressed genes in multiple brain regions. However, the brain’s heterogeneous nature prevents identification of relevant cell types. This study analyzed single-nuclei transcriptomics of ~275,000 nuclei from frozen human postmortem dorsolateral prefrontal cortex samples from males wit...

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Literature Corpus work: df6c7e51-3b87-5096-a104-4fae489b4797
DOI: 10.1101/2020.07.29.227355

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