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Article

Single-nucleus RNA sequencing of the midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypes

2022-06-23

Abstract excerpt

<title>Abstract</title> <p>The midbrain is an important brain region for the study of schizophrenia in view of its reported dopamine pathophysiology and observed neuroimmune changes associated with schizophrenia. Besides the dopaminergic system, the midbrain contains other cell types that may be involved in schizophrenia pathophysiology. The neurovascular hypothesis of schizophrenia postulates that both the neuro...

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Literature Corpus work
b6d56d7a-daa7-5453-8eba-aefc000a4d8c
DOI
10.21203/rs.3.rs-1780478/v1
Open publication

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Single-nucleus RNA sequencing of the midbrain blood-brain barrier cells in schizophrenia reveals subtle transcriptional changes with overall preservation of cellular proportions and phenotypesDOI 10.21203/rs.3.rs-1780478/v1
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