Article

NUP98 rearrangements in adult AML patients: Evaluation of clinical implications and identification of novel fusion partners

2025-06-30

Abstract excerpt

<title>Abstract</title> <p> <italic>NUP98</italic> rearrangements represent a distinct, high-risk subtype of acute myeloid leukemia (AML), particularly in pediatric patients. However, their prevalence, genetic features, and clinical implications in adult AML remain poorly characterized. Using targeted-capture sequencing, we identified 41 cases with <italic>NUP98</italic> rearrangements among 1569 AML cases, r...

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Literature Corpus work: 100cce6a-4fcc-5a09-845e-635973c0a1e3
DOI: 10.21203/rs.3.rs-6926420/v1

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