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Nucleoporin 98 Rearrangements in Acute Leukemia: A Genomic Landscape Study

29 Jul 2026

Abstract excerpt

Nucleoporin 98 rearrangements (NUP98re) occur in a wide range of hematologic malignancies including acute leukemias with a variety of fusion partners. NUP98re is associated with adverse prognosis, especially in children. We aimed to better understand the genomics of acute leukemias with NUP98re including fusion partners and co-occurring genomic alterations (GA). Results from 5905 patients with acute leukemia...

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PMID: 42522886
DOI: 10.1002/hon.70231

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