Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Landscape of somatic mutations and clonal evolution in NUP98‐rearranged adult acute myeloid leukaemia

19 Dec 2024

Abstract excerpt

Acute myeloid leukaemia with NUP98 rearrangement (AML-NUP98) has been previously described in paediatric patients, and the clinical significance in adult AML patients remains largely unexplored. In this study, we identified specific partner fusion genes and examined somatic co-mutations and clonal evolution longitudinally in adult AML-NUP98 patients. Our comprehensive analysis provides an understanding of NUP98...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cancer Genomics and Diagnostics
Share to Protein Degradation and Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39701595
DOI: 10.1111/bjh.19962

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Landscape of somatic mutations and clonal evolution in NUP98‐rearranged adult acute myeloid leukaemiaPMID 39701595Read ↗

NUP98 rearrangements in adult AML patients: evaluation of clinical implications and identification of novel fusion partners.Semantic proximity Read ↗

Comprehensive molecular and clinical characterization of NUP98 fusions in pediatric acute myeloid leukemia.Semantic proximity Read ↗

NUP98 Rearrangements in AML: Molecular Mechanisms and Clinical ImplicationsSemantic proximity Read ↗

NUP98 rearrangements in adult AML patients: Evaluation of clinical implications and identification of novel fusion partnersSemantic proximity Read ↗

Targeted gene sequencing and transcriptome sequencing reveal characteristics of NUP98 rearrangement in pediatric acute myeloid leukemia.Semantic proximity Read ↗

Comprehensive mutational profiling and clinical outcome of adult acute myeloid leukemia patients with NUP98 rearrangement.Semantic proximity Read ↗

Nucleoporin 98 Rearrangements in Acute Leukemia: A Genomic Landscape StudySemantic proximity Read ↗

NUP98 is rearranged in 3.8% of pediatric AML forming a clinical and molecular homogenous group with a poor prognosis.Semantic proximity Read ↗

Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98 -rearranged leukemiaSemantic proximity Read ↗

NUP98 oncofusions in myeloid malignancies: An update on molecular mechanisms and therapeutic opportunitiesSemantic proximity Read ↗

Clinicogenetic characteristics and outcomes of children with NUP98-rearranged acute myeloid leukaemia: A single-centre cohort study of 32 cases.Semantic proximity Read ↗

Identification of novel NUP98 fusion partners and comutations in acute myeloid leukemia: an adult cohort study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.