Article

Target-specific precision of CRISPR-mediated genome editing

2018-08-09

Abstract excerpt

<h4>ABSTRACT</h4> The CRISPR-Cas9 system has successfully been adapted to edit the genome of various organisms. However, our ability to predict editing accuracy, efficacy and outcome at specific sites is limited by an incomplete understanding of how the bacterial system interacts with eukaryotic genomes and DNA repair machineries. Here, we performed the largest comparison of indel profiles to date, examining over...

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Literature Corpus work: 0fc9b890-40b5-56cd-ba33-186971ca98c5
DOI: 10.1101/387027

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