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Genetically proxied PCSK9 inhibition provides indication of lower prostate cancer risk: a Mendelian randomization study

2022-04-19

Abstract excerpt

<h4>Background</h4> Prostate cancer (PrCa) is the second most prevalent malignancy in men worldwide. Observational studies have linked the use of low-density lipoprotein cholesterol (LDL-c) lowering therapies with reduced risk of PrCa, which may potentially be attributable to confounding factors. In this study, we performed a drug target Mendelian randomization (MR) analysis to evaluate the association of genetica...

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Literature Corpus work
0fb98f67-bd83-52d7-9a0c-bfc9189039a1
DOI
10.1101/2022.04.18.22274003
Open publication

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Genetically proxied PCSK9 inhibition provides indication of lower prostate cancer risk: a Mendelian randomization studyDOI 10.1101/2022.04.18.22274003
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