Article

Lipids, lipid-modifying drug Target genes and Bladder cancer: a Mendelian randomization study

2023-11-07

Abstract excerpt

<h4>Background: </h4> Bladder cancer (BLCA) is among the 10th most common malignancies with high morbidity and mortality. Statins and emerging lipid-modifying drug targets may also show potential in treating BLCA and lowering cholesterol levels. Mendelian randomization (MR) analysis provides insights into the causal relationship between exposure and disease. This study aimed to explore genetically predicted lipid...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ae1a80f6-04a1-5077-ba09-d0aa1955f657
DOI: 10.21203/rs.3.rs-3541205/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Lipids, lipid-modifying drug Target genes and Bladder cancer: a Mendelian randomization studyDOI 10.21203/rs.3.rs-3541205/v1Read

Unveiling the association between HMG-CoA reductase inhibitors and bladder cancer: a comprehensive analysis using Mendelian randomization, animal models, and transcriptomics.Semantic proximity Read

Assessing the role of statin therapy in bladder cancer: evidence from a Mendelian Randomization studySemantic proximity Read

Causal association between lipid-lowering drugs and cancers: A drug target Mendelian randomization study.Semantic proximity Read

Causal relationship between lipid-lowering drugs and ovarian cancer, cervical cancer: a drug target mendelian randomization study.Semantic proximity Read

Higher genetically predicted triglyceride level increases the bladder cancer risk independent of LDL and HDL levels.Semantic proximity Read

Causal association of smoking, blood lipids, and bladder cancer: Insights from a multivariable and mediation mendelian randomization investigationSemantic proximity Read

Genetically proxied PCSK9 inhibition provides indication of lower prostate cancer risk: a Mendelian randomization studySemantic proximity Read

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancersSemantic proximity Read

Comprehensive Mendelian randomization analysis of low-density lipoprotein cholesterol and multiple cancersSemantic proximity Read

Blood lipid genetic scores, the HMGCR gene and cancer risk: a Mendelian randomization study.Semantic proximity Read

A genetic perspective on the relationship between circulating proteins and bladder cancer: a study from drug-targeted Mendelian randomizationSemantic proximity Read

Associations of blood lipids and LDL cholesterol lowering drug-targets with colorectal cancer risk: a Mendelian randomisation study.Semantic proximity Read