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Article

Association between genetically proxied HMGCR inhibition and male reproductive health: A Mendelian randomization study.

Medicine - 29 Sept 2023

Yan Zhaoqi, Xu Yifeng, Li Keke, Liu Liangji

Abstract excerpt

BACKGROUND: The causal associations between statin use and male sex hormone levels and related disorders have not been fully understood. In this study, we employed Mendelian randomization for the first time to investigate these associations. METHODS: In two-sample Mendelian randomization framework, genetic proxies for hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR) inhibition were identified as variants in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 37773823
DOI: 10.1097/MD.0000000000034690
PMCID: PMC10545124

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