Article

Genetically-proxied anti-diabetic drug target perturbation and risk of cancer: a Mendelian randomization analysis

2022-10-26

Abstract excerpt

<h4>Aims/hypothesis</h4> Epidemiological studies have generated conflicting findings on the relationship between anti-diabetic medication use and cancer risk. Naturally occurring variation in genes encoding anti-diabetic drug targets can be used to investigate the effect of their pharmacological perturbation on cancer risk. <h4>Methods</h4> We developed genetic instruments for three anti-diabetic drug targets (per...

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Literature Corpus work: ba6bd3d9-104a-5ff4-9775-ec7fa5116481
DOI: 10.1101/2022.10.24.22281370

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